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Monkeypox or MPXV: Management & Medications

Treatment - Management

(AMA) There is no treatment specifically for monkeypox, but because the monkeypox and smallpox viruses are closely related, drugs and vaccines developed to protect against smallpox may be used to prevent and treat monkeypox virus infections.  Treatment will depend on how sick someone gets or whether they are likely to get severely ill. Most people with monkeypox recover fully within 2 to 4 weeks without the need for treatment. 



(AMA) The antiviral drug tecovirimat (also known as TPOXX) was developed to fight smallpox, but the U.S. Food and Drug Administration allows CDC to use it to treat monkeypox during an outbreak.


Immune Globulin

  • Intravenous Immune Globulin (VIGIV)  is licensed by FDA for treating complications from smallpox vaccination. CDC has permission to use of VIGIV for the treatment of orthopoxviruses, including monkeypox, during an outbreak.