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All Things Covid-19: General & News

Arizona Case Load and Mortality (COVID Act Now)

COVID-19 News Updates

Oxford team begins vaccine trials in Brazil and South Africa to determine efficacy  BMJ News 29-JUN-2020
Social distancing alters the clinical course of COVID-19 in young adults: A comparative cohort studClin Infect Diseases 29-JUN-2020
Diagnostic strategies for SARS-CoV-2 infection and interpretation of microbiological results  Clin Microbiol & Infect  25-JUN-2020
COVID-19: Timing is critical for antibody tests, finds Cochrane review  BMJ 25-JUN-2020
Risk factors for 2019 novel coronarvirus disease (COVID-19) patients progressing to critical illness: a systematic review and meta-analysis.  Aging  24-JUN-2020
Comparison of epidemiological variations in COVID-19 patients inside and outside of China - A meta-analysis  Front Public Health  24-JUN-2020
What is the evidence to support the 2-metre social distancing rule to reduce COVID-19 transmission? CEBM. 22-JUN-2020
Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVD-19 patients  Jnl of Infect  20-JUN-2020
Identifying airborne transmission as the dominant route for the spread of COVID-19.  Proc Natl Acad Sci USA 13-JUN-2020
Top U.S. Coronavirus Hot Spots are all Indian Lands - New York Times 30-MAY-2020
Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic. Early release (not final version):  Emerging Infectious Diseases July 2020
AstraZeneca partners with Oxford University to product COVID-19 vaccine; The Guardian news article; 30-APR-2020

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial The Lancet  29-APR-2020

Updates on What ACS Reported: Emerging Evidences of COVID-19 with Nervous System Involvement ACS Chem Neurosci 28-APR-2020

Comparison of Four Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 in Nasopharyngeal Specimens  Jnl Clin Microbiol  27-APR-2020

FDA issues Emergency Use Authorization permitting emergency usage of Stryker Sterizone VP4 Sterilizer with N95 Respirator Decontamination Cycle to decontaminate N95 or N95-equivalent respirators in hospital setting, enabling reuse by clinicians 

Quarantine measures reported to reduce incidence and mortality during COVID-19 pandemic (Cochrane)

Prevalence of gastrointestinal symptoms about 18% in patients with confirmed COVID-19

Clinical Characteristics of 3,062 COVID-19 Patients: A Meta-Analysis

SAR-CoV-2 viral shedding estimated to peak before or at onset of symptoms in patients with COVID-19.
FDA Emergency Use Authorization regarding B. Braun Space and Outlook Pumps 16-APR-2020
More on Chloroquine/Azithromycin.  And on Dr. Raoult.  Opinion/Commentary. Science Translational Medicine.

Loss of smell and taste a key symptom for COVID-19 cases

Humans, Viruses, and the Eye—An Early Report From the COVID-19 Front Line  JAMA Ophthalmology 31-MAR-2020 

Severe outcomes among patients with coronavirus disease 2019 - United States - Feb 12 - March 16, 2020 (CDC)

Surviving Sepsis Campaign Guidelines on the management of critically ill adults with coronavirus disease 2019  Critical Care Medicine 28-MAR-2020

COVID-19 Situation Reports (Johns Hopkins)

CDC Situation Summary

Maricopa County Public Health

COVID-19 Summaries / Broad View


Why use it?

National Institutes of Health, or UpToDate, or Dynamed, or British Medical Journal or Infectious Diseases Society of America

Clinical overviews; some identify evidence quality

Quickly find specific focus area (e.g., diagnosis)

Updates are noted/highlighted

Society guidelines (UpToDate) International coverage, listed by medical specialties & country.
CDC Situation Summary Information for Health Care Professionals
COVID-19 Information Portal (EBSCO) Global scope, leans toward government policy & news

COVID-19 Clinical Decision-Making


Why use it?

Physician's Guide + Resources (American College of Physicians) Current education on all clinical aspects of COVID-19. Updates are clearly posted. CME credit available
A Composite Reference Standard for COVID-19 Diagnostic Accuracy Studies: A roadmap (CEBM, University of Oxford) Diagnosis support.  The group is developing a reference standard for diagnosis and aims to decrease the number of false negative rRT-PCRs
Guidelines (Elsevier) Clinical guidelines for therapy, labs, testing, PPE, ventilators
Treatment algorithms (BMJ Best Practice) Clinical decision support for suspected and confirmed COVID-19
Oxford COVID-19 Evidence Service (Univ. of Oxford Centre for Evidence-Based Medicine) Rapid reviews of primary care questions; updates noted.
Clinical Care FAQs - Your Questions Answered ECRI answers to questions from health care workers

COVID-19 Co-Existing Conditions

Resource Why Use It?
Management of coexisting conditions in the context of COVID-19  (BMJ Best Practice) Regular updates are plainly identified.  Addresses broad range of conditions as more becomes known.
COVID-19 and Patients wth Cancer (Dynamed) Clinical decision support
COVID-19 and Pregnant Patients (Dynamed) Clinical decision support
COVID-19 and patients with CKD and ESRD (Dynamed) Clinical decision support
COVID-19 and Special Populations (Dynamed) Clinical decision support re: cancer, coagulopathies, CV disease, kidney disease, HIV infection, neurological conditions, pediatrics, & pregnancy.

COVID-19 literature: drink from the firehose


Why use it?

LitCOVID (National Library of Medicine) Updated every 24 hours as COVID-19-related articles are indexed in PubMed. Easily narrow focus to topics like transmission, case reports, diagnosis, forecasting, treatment.
Global literature on coronavirus disease (World Health Organization) Global perspective, easily narrow search by major subjects, type of study, language, and clinical focus.
PubMed COVID-19 Search (National Library of Medicine) Use this basic COVID-19 search strategy as a starting point for your own searches.