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All Things Covid-19: Critical Illness

Critical Illness Articles

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A prospective stud of neurologic disorders in hospitalized COVID-19 patients in New York City. American Academy of Neurology  05-OCT-2020
Recommendations for prehospital airway management in patients with suspected COVID-19 infection West J Emerg Med  30-JUL-2020
Thrombotic circuit complications during venovenous extracorporeal membrane oxygenation in COVID-10. Jnl Thromb Thrombolysis  13-JUL-2020
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents NEJM  29-JUN-2020
Risk factors for 2019 novel coronarvirus disease (COVID-19) patients progressing to critical illness: a systematic review and meta-analysis. Aging  24-JUN-2020

OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients.

Preprint (not yet peer reviewed) medRxiv 07-MAY-2020
"Silent Hypoxia" COVID-19 patients with respiratory failure: what can we learn from aviation medicine? Br Jnl Anaesthes 18-APR-2020
"Silent Hypoxia" Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations Br Jnl Anaesthes 10-APR-2020
Mysterious Heart Damage, Not Just Lung Troubles, Befalling COVID-19 Patients Kaiser Health News 06-APR-2020
Surviving Sepsis Campaign: guidelines on the management of critically ill adults with coronavirus disease 2019  (COVID-19) Critical Care Medicine 28-MAR-2020
COVID-19 in critically ill patients in the Seattle region - Case series NEJM 30-MAR-2020
Coronavirus (COVID-19): Evidence relevant to critical care Cochrane Special Collections.  Updated continually.

Lung Recruitability in SARS-CoV-2 Associated Acute Respiratory Distress Syndrome: A Single-center, Observational Study

Am J Resp & Crit Care Med 

Rising to the Challenge of the Novel SARS-coronavirus-2 (SARS-CoV-2): Advice for Pulmonary and Critical Care and an Agenda for Research

Am J Resp & Crit Care Med 

Ventilatory Ratio in Hypercapnic Mechanically Ventilated Patients with COVID-19 Associated ARDS

Am K Resp & Crit Care Med Case Series

Critical Illness Resources

Resource

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(VitalTalk) A portal to videos and print materials for building skills for talking with patients, families, and each other in challenging situations. 
Ad-Hoc COVID-19 Treatment Team algorithms & protocols.   Yale University; color coded guidance sheets, from "non-severe"  to severe disease. Updated as reliable information emerges. 03-AUG-2020
Nutrition Therapy in the Patient with COVID-19 Disease Requiring ICU Care Society of Critical Care Medicine & the American Society for Parenteral and Enteral Nutrition.   Updated 01-APR-2020
COVID Ready Communication Playbook  Practical & specific advice on how to talk about difficult COVID-related topics.  Continuum of care.  Multiple languages. Provided by VitalTalk, a nonprofit startup dedicated to making "communication skills for serious illness part of every clinician's toolbox."  JUN 2020
COVID-19 cytokine storm and novel truth. Medical Hypotheses NOV 2020  "COVID-19 is not 'pneumonia' nor 'ARDS'"
Screening & Treatment for Post-Intensive Care Syndrome after Discharge of Patients with COVID-19 ECRI.  MAY 2020
Factors Informing Clinical Decisions about Ventilator use During Ventilator Shortages in an Infectious Disease Pandemic ECRI. 27-APR-2020.  "Evidence raises concerns."
Evidence-Based Strategies for Weaning Patients with COVID-19 from Mechanical Ventilation ECRI.  April 2020.
Mechanical Ventilation Protocol Summary ARDSnet NIH NHLBI ARDS Clinical Network
Not so fast using CPAPs in place ventilators. They could spread coronavirus California Healthline March 27, 2020
ACP Resources: Clinical Care - Hospital Frequently updated. UW Medicine downloadable PDFs, donning/doffing PPE video, ICU guidance for the non-intensivist, capacity management guide, hospital preparedness video
ACP Resources: Clinical Care - Supportive + Intensive Care Frequently updated. Supportive care definitions, ICU guidance for the non-intensivist, point-of-care ultrasound video hospital medicine playbook for COVID-19
BMJ Best Practices "Complications" British Medical Journal Timeframe & likelihood of ARDS, liver/kidney/cardiac injury, secondary infection, sepsis, DIC, pregnancy-related complications, rhabdomyolysis
Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected Downloadable PDF, WHO Guidelines
BMJ Best Practices Treatment Algorithms British Medical Journal Algorithms for suspected & confirmed COVID-19 and severe illness
UpToDate Coronavirus Disease 2019 (COVID-19) Section on "Hospital care"