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All Things Covid-19: General & News

COVID-19 Vaccine Tracker: constantly updating US & international vaccination administration stats. (Bloomberg News)


Arizona COVID Situation (CovidActNow.org) (Will not load in IE browsers)

COVID-19 Clinical Decision-Making

Resource

Why use it?

Physician's Guide + Resources (American College of Physicians) Current education on all clinical aspects of COVID-19. Updates are clearly posted. CME credit available
COVID Ready Communication Playbook (VitalTalk) JUN 2020 Has practical advice on how to talk with patients/families about difficult COVID-related topics.  Continuum of care.  Multiple languages.
A Composite Reference Standard for COVID-19 Diagnostic Accuracy Studies: A roadmap (CEBM, University of Oxford) Diagnosis support.  The group is developing a reference standard for diagnosis and aims to decrease the number of false negative rRT-PCRs
Guidelines (Elsevier) Clinical guidelines for therapy, labs, testing, PPE, ventilators
Treatment algorithms (BMJ Best Practice) Clinical decision support for suspected and confirmed COVID-19
Oxford COVID-19 Evidence Service (Univ. of Oxford Centre for Evidence-Based Medicine) Rapid reviews of primary care questions; updates noted.
Clinical Care FAQs - Your Questions Answered ECRI answers to questions from health care workers

COVID-19 News Updates

6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records (The Lancet Psychiatry 06-APR-2021.)
COVID-19 Trends among school-aged children - United States, March 1 - September 19, 2020  MMWR OCT 2020
Allergic reactions including anaphylaxis after receipt of the first dose of Pfizer-BioNTech COVID-19 vaccine. JAMA 21-JAN-2021
Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial JAMA 21-JAN-2021
Association between statin use and outcomes in patients with coronavirus disease 2019 (COVID-19): A nationwide cohort study BMJ Open 13-JAN-2021
New NIH COVID-19 research includes insights on coronavirus' effect on patients' brains; blood thinner trial enrollment paused.  AHA 04-JAN-2021
Emergence of a highly fit SARS-CoV-2 variant. 31-DEC-2020.  NEJM
COVID-19 conspiracies and beyond: How physicians can deal with patients' misinformation 30-DEC-2020 JAMA
A neutralizing monoclonal antibody for hospitalized patients with COVID-19. 22-DEC-2020. NEJM  LY-CoV555, when given along with remdesivir, did not demonstrate efficacy.
Development and external validation of a prognostic tool for COVID-19 critical disease 09-DEC-2020 PLoS One. The tool accurately predicted COVID-19 critical disease risk using comorbidities and presenting vital signs and lab values.
Early empirical assessment of the N501Y mutant strains of SARS-CoV-2 in the UK, Oct to Nov 2020. Article pre-print. It may be 75% more transmissible than the previous lineage, but there does not appear to be significant spread outside of the UK despite sporadic cases in Wales, Australia, Spain, and the US.
Genetic Screens Identify Host Factors for SARS-CoV-2 and common cold coronaviruses 09-DEC-2020
Four COVID-19 Lessons for Achieving Health Equity JAMA Forum 08-DEC-2020

Assessment of Evidence for COVID-19-Related Treatments  American Society of Health System Pharmacists (ASHP) Look for "Evidence Table" on the webpage  01-DEC-2020

I am an emergency and critical care physician.  I had COVID-19 infection twice and I'm tired. (Kevin MD.com)
COVID-19 Disinfectants : Try "browse all" to see full list of disinfectants, contact time required, active ingredients, and more.  (EPA)
Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project.)   Article Pre-Print  24-NOV-2020
Evaluation of 7 commercial RT-PCR kits for COVID-19 testing in pooled clinical specimens.  Jnl of Medical Virology 24-NOV-2020
Psychological Entitlement predicts noncompliance with the health guidelines of the COVID-19 pandemic Pers Individ Dif 29-OCT-2020
SARS-CoV-2 isolates in Los Angeles are similar to European isolates, suggesting the virus got to L.A. via Europe. Analysis of genomic characteristics and transmission routes of patients with confirmedSARS-CoV-2 in southern California during the early stage of the US COVID-19 pandemic.  JAMA Network Open 07-OCT-2020

COVID-19 literature: drink from the firehose

Resource

Why use it?

LitCOVID (National Library of Medicine) Updated every 24 hours as COVID-19-related articles are indexed in PubMed. Easily narrow focus to topics like transmission, case reports, diagnosis, forecasting, treatment.
Global literature on coronavirus disease (World Health Organization) Global perspective, easily narrow search by major subjects, type of study, language, and clinical focus.
PubMed COVID-19 Search (National Library of Medicine) Use this basic COVID-19 search strategy as a starting point for your own searches.

COVID-19 Summaries / Broad View

Resource

Why use it?

National Institutes of Health, or UpToDate, or Dynamed, or British Medical Journal or Infectious Diseases Society of America

Clinical overviews; some identify evidence quality

Quickly find specific focus area (e.g., diagnosis)

Updates are noted/highlighted

Society guidelines (UpToDate) International coverage, listed by medical specialties & country.
CDC Situation Summary Information for Health Care Professionals
COVID-19 Information Portal (EBSCO) Global scope, leans toward government policy & news
Cochrane COVID Reviews Trusted source of systematic reviews